JUL 26, 2018

New paper is comingCongrats!

N. Zhang, Z. M. Yu, X. H. Yang, Y. Zhou, Q. Tang, P. Hu, J. Wang, S. L. Zhang, M. W. Wang, and Y. He, Difuran-substituted Quinoxalines as a Novel Class of PI3K<alpha> H1047R Mutant Inhibitors: Synthesis, Biological Evaluation and Structure-activity Relationship,  Eur. J. Med. Chem., 2018, Accepted

JUL 21, 2018

New paper is coming! Congrats!

Z. H. Lin, X. B. Xu, S. Zhao, X. H. Yang, J. Guo, Q. Zhang, C. M. Jing, S. Chen and Y. He, Total Synthesis and Antimicrobial Evaluation of Natural Albomycins against Clinical Pathogens, Nat. Commun., 2018, Accepted 

JUL 17, 2018

Welcome Yifan Zhong ( Ph.D. student ) join in our family.

JUL 11, 2018

  1. Welcome new members!

Welcome Guoxin Wei ( Ph.D. student ), Xue Huang ( Technician ), Xumei Wen ( MS student ), Siyu Li ( MS student ),Meng Tang ( MS student ),Shenghui Liang ( MS student ) join in our family. You are carrying the hopes of the lab and we wish you have fruitful and amazing time with us!

2. New paper is coming! 

Z. P. Wang, S. C. Xiang, P. L. Shao, Y. He, Catalytic Asymmetric [3 + 2] Cycloaddition Reaction Between Aurones and Isocyanoacetates: Access to Spiropyrrolines via Silver CatalysisJ. Org. Chem., 2018, Accepted 

JUL 9, 2018

Congratulations on the graduation:
Ph.D.: Zhipeng Wang, Yesu Addepalli, Srinivasa Rao Allu and Chandraiah Lagishetti; MS: Zirui Li, Minghui Zhou, Qiang Zheng, Yunshan Li and Zimeng Zhao.
Best wishes to all of them for a successful career and a bright future!

JUN 5, 2018

Chemical & Engineering News has a special report on Prof. Yun He.Opportunities in academia and industry call chemist from China to the U.S.—and back again

JUN 1, 2018

Prof. Yun He attended Nature Conference “Countering Antimicrobial Resistance” (May 28-29, 2018) in Beijing, and presented “Total Synthesis and Antimicrobial Evaluation of Natural Albomycins Against Clinical Pathogens”.

MAR 16, 2018

New paper is coming!“Synthesis of Bioactive 3,4-Dihydro-2H-naphtho[2,3-b] [1,4]oxazine-5,10-dione and 2,3,4,5-Tetrahydro-1H-naphtho[2,3-b]azepine-6,11-dione Derivatives via Copper-catalysed Intramolecular Coupling Reaction” J. Org. Chem.2018, ASAP

MAR 2, 2018

“Synthesis of novel ring-contracted artemisinin dimers with potent anticancer activities” E. J. Med. Chem., 2018ASAP

FEB 26, 2018

 New paper is coming! “Synthesis and anticancer activity evaluation of novel azacalix[2]arene[2]pyrimidines” E. J. Med. Chem., 2018ASAP

FEB 2, 2018

New year has come! You all are worthy to have a great celebration party in XiYong Hotel. Enjoy yoursleves to the most!

JAN 8, 2018

New paper is coming! “Construction of Polycyclic Indole Derivatives via Multiple Aryne Reactions with Azaheptafulvenes” Org. Lett.2017. ASAP

JAN 5, 2018

Welcome Yanfei QIU join in our family.

SEP 30, 2017

“Enantioselective Synthesis of 4-Thioetherpyrrolidine Derivatives via [3 + 2] Cycloaddition of α-Thioacrylates with Isocyanoacetates” J. Org. Chem.2017, ASAP.

SEP 21, 2017

Palladium-catalyzed oxidative arylacetoxylation of alkenes: synthesis of indole and indoline derivatives” Chem. Commun.2017Advance Article DOI:10.1039/C7CC06448A

SEP 18, 2017

[3 + 2] Cycloaddition of Azaoxyallyl Cations with Cyclic Ketones: Access to Spiro-4-oxazolidinones” J. Org. Chem.2017, ASAP. DOI: 10.1021/acs.joc.7b01728

AUG 29, 2017

Welcome Jie Ji and Ji-Zhou Feng join in our family.

AUG 26, 2017

“Catalytic Asymmetric Synthesis of Pyrrolidine Derivatives Bearing Heteroatom-Substituted Quaternary Stereocenters” Org. Chem. Front., 2017. ASAP

AUG 18,2017

“A Unified Modular Synthetic Strategy for Dictyodendrins F, H, I, and G”. Org. Lett. 2017, ASAP

AUG 1, 2017

Q. Liu, P. Hu and Y. He, “Asymmetric Total Synthesis of Nannocystin A” . J. Org. Chem. 2017ASAP.

jun 11, 2017

For congratulations on the graduation of Zhonglin Zang; Xiaobo Xu;  Zhanlong Wang; Jiangsheng Gao; Xiaojiao Peng; Meiqiong Tang, we hold a party in xiyue hotel.

MAY 24, 2017

Enantioselective Synthesis of Tetrahydropyridines/Piperidines via Stepwise [4 + 2]/[2 + 2] Cyclizations” Org. Lett., 2017. ASAP.

MAY 22, 2017

Welcome Zimeng Zhao, Yuan Jiang join in our family.

MAY 19, 2017

Ru Jian. Ma, the VP of WuXi AppTec,paid a visit to ChongQing University on May, 19, 2017. And he was invited to give us a presentation entitled “Efficient organic synthesis in R & D service enterprises”

MAY 13, 2017

Prof. Steven L. Castle of Brigham Young University, paid a visit to ChongQing University on May, 13, 2017. And he was invited to give us a presentation entitled “New Strategies for the Synthesis of Unusual Peptides”

MAY 3, 2017

Another new paper is coming! “Dually responsive amphiphilic block copolymer with oxidation-responsiveness and tuneable LCST behaviours” Materials Letters. 2017, ASAP.

MAR 4, 2017

Another new paper is coming! “Synthesis of Spiro-Dihydroquinoline and Octahydrophenanthrene Derivatives via Palladium-Catalyzed Intramolecular Oxidative Arylation” Org. Lett. 2017, ASAP

MAR 2, 2017

Another new paper is coming! “Stevens rearrangement of thioethers with arynes: a facile access to multi-substituted β-keto thioethers” Org. Biomol. Chem., 2017, Advance Article

feb 16, 2017

Welcome Wenjing Yu, Xianyu Lu (visiting student from Shandong University) join in our family.

JAN 18, 2017

Another new paper is coming! “Selective Aza Diels-Alder and Tandem [4+2]/[2+2] Cycloaddition Reactions of Arynes with N-Sulfonyl Ketimines” J. Org. Chem., 2017ASAP. 

JAN 14, 2017

New year has come! You all are worthy to have a great celebration party in Holiday Inn Chongqing University Town. Enjoy yoursleves to the most!

dec 6, 2016

Another new paper is coming! Dual thermo/oxidation-responsive block copolymers with self-assembly behaviour and synergistic release” Reactive and Functional Polymers. 2016, ASAP. 

NOV 18, 2016

Another new paper is coming!

“Insertion of Arynes into P–O Bonds: One-Step Simultaneous Construction of C–P and C–O Bonds” Org. Lett., 2016. ASAP

NOV 10, 2016

Another new paper is coming!
“Total Syntheses of Anti-HIV Cyclodepsipeptides Aetheramides A and B” J. Org. Chem. 2016. ASAP

Sep 21, 2016

Another new paper is coming!

“Catalytic Multisite-Selective Acetoxylation Reactions at sp2 vs sp3 C–H Bonds in Cyclic Olefins” Org. Lett., 2016, 18 (19), 5014–5017.

SEP 17, 2016

Another new paper is coming!

“Formal [3+2] Cycloaddition of α‐Unsubstituted Isocyanoacetates and Methyleneindolinones: Enantioselective Synthesis of Spirooxindoles” Org. Chem. Front. 2016, ASAP

Sep 21, 2016

Another new paper is coming!

“Catalytic Multisite-Selective Acetoxylation Reactions at sp2 vs sp3 C–H Bonds in Cyclic Olefins” Org. Lett. 2016, 18 (19), 5014–5017

SEP 7, 2016

Another new paper is coming!

“Asymmetric Total Syntheses of Aetheramides and Their Stereoisomers: Stereochemical Assignment of Aetheramides” Org. Lett2016, 18 (18), 4718–4721.

Aug 29, 2016

Another new paper is coming!

“Synthesis of Dihydrophenanthridines and Oxoimidazolidines from Anilines and Ethylglyoxylate via Aza Diels–Alder Reaction of Arynes and KF-Induced Annulation” Org. Lett. 2016, 18 (18), 4546–4549.

Jul 19, 2016

Another new paper is coming!

“Transition-Metal-Free Cascade Synthesis of 4-Quinolones: Umpolung of Michael Acceptors via Ene Reaction with Arynes” Org. Lett., 2016, 18 (15), 3818–3821.

Jul 15, 2016

Another new paper is coming!

“A practical and efficient route to heteraphanes: synthesis of structurally simplified analogues of ansamycins” RSC Adv., 2016, 6, 68199-68203.

Jun 30, 2016

New generation comes!

Let’s welcome our new M.S. graduate students: Qin Su, Qi Wu, Qing Tang, Wenxi Li, Jia Jiang, Zhimei Yu join in our big family! You are carrying the hopes of the lab and we wish you have fruitful and amazing time with us!

Jun 21, 2016

Another new paper is coming!

Total synthesis of calothrixins and their analogues via formal [3+2] cycloaddition of arynes and 2-aminophenanthridinedione“ Tetrahedron Lett. 2016, 57, 3481–3484.

Welcome Yanfang Wang (visiting student from Xinjiang) join in our family.

May 5, 2016

Another new paper is coming!

“Synthesis of Carbazolequinones by Formal [3 + 2] Cycloaddition of Arynes and 2-Aminoquinones” Org. Lett. 2016, 18 (10), 2499–2502.

Apr 26, 2016

Another new paper is coming!

“Synthesis of Dimeric Oxazoles, Piperidines and Tetrahydroisoquinolines from N-Substituted 2-Oxazolones” Chem. Eur.J. 2016, 22, 7696 –7701. 

Apr 10, 2016

A wonderful dayout in Lianhua Lake. Hope you all enjoyed the sunshine, Majiang and of course, Barbecue.

Jan 9, 2016

New year has come! You all are worthy to have a great celebration party in Lotus Hotel (5 star). Enjoy yoursleves to the most!